Summary: The Fueter-Sce theorem provides a procedure to obtain axially monogenic functions, which are in the kernel of generalized Cauchy-Riemann operator in \({\mathbb{R}}^{n+1} \). This result is obtained by using two operators. The first one is the slice operator, which extends holomorphic functions of one complex variable to slice monogenic functions in \(\mathbb{R}^{n+1} \). The second one is a suitable power of the Laplace operator in \(n + 1\) variables. Another way to get axially monogenic functions is the generalized Cauchy-Kovalevskaya (CK) extension. This characterizes axial monogenic functions by their restriction to the real line. In this paper, using the connection between the Fueter-Sce map and the generalized CK-extension, we explicitly compute the actions \(\Delta_{\mathbb{R}^{n+1}}^{\frac{n-1}{2}} x^k\), where \(x \in \mathbb{R}^{n+1} \). The expressions obtained is related to a well-known class of Clifford-Appell polynomials. These are the building blocks to write a Taylor series for axially monogenic functions. By using the connections between the Fueter-Sce map and the generalized CK extension, we characterize the range and the kernel of the Fueter-Sce map. Furthermore, we focus on studying the Clifford-Appell-Fock space and the Clifford-Appell-Hardy space. Finally, using the polyanalytic Fueter-Sce theorems, we obtain a new family of polyanalytic monogenic polynomials, which extends to higher dimensions the Clifford-Appell polynomials.