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Decylcitrate synthase

From Wikipedia, the free encyclopedia
decylcitrate synthase
Identifiers
EC no.2.3.3.2
CAS no.9068-72-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

Decylcitrate synthase (EC 2.3.3.2) is an enzyme that catalyzes the chemical reaction in enzymology.

lauroyl-CoA + H2O + oxaloacetate (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA

The 3 substrates of this enzyme are lauroyl-CoA, H2O, and oxaloacetate, whereas its two products are (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate and CoA.

This enzyme belongs to the family of transferases, specifically those acyltransferases that convert acyl groups into alkyl groups on transfer. The systematic name of this enzyme class is dodecanoyl-CoA:oxaloacetate C-dodecanoyltransferase (thioester-hydrolysing, 1-carboxyundecyl-forming). Other names in common use include 2-decylcitrate synthase, (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate oxaloacetate-lyase, and (CoA-acylating).

References

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  • Mahlen A, Gatenbeck S (1968). "A metabolic variation in Penicillium spiculisporum Lehman. II Purification and some properties of the enzyme synthesizing (--)-decylcitric acid". Acta Chem. Scand. 22 (8): 2617–2623. doi:10.3891/acta.chem.scand.22-2617. PMID 5719165.
  • Mahlen A (1971). "Properties of 2-decylcitrate synthase from Penicillium spiculisporum Lehman". Eur. J. Biochem. 22 (1): 104–114. doi:10.1111/j.1432-1033.1971.tb01520.x. PMID 5099208.