| dbo:abstract
|
- Als Kurloff-Zellen bezeichnet man eine Unterform der weißen Blutkörperchen bei Meerschweinchen. Es handelt sich um mononukleäre Zellen, vor allem Lymphozyten, die durch etwa 8 µm große, in den hämatologischen Standardfärbungen rötliche Einschlusskörperchen (Kurloff-Körperchen) gekennzeichnet sind. Man vermutet, dass Kurloff-Zellen eine besondere Ausprägung der NK-Zellen sind. Der Gehalt des Blutes an Kurloff-Zellen steht bei weiblichen Tieren in Zusammenhang mit dem Östrogenspiegel. Während der Trächtigkeit können sie bis zu 4 % der weißen Blutkörperchen ausmachen. (de)
- Kurloff cells (also known as Foà-Kurloff cells,) were described as mononuclear cells in the peripheral blood and organs of the guinea pig, capybara, paca, agouti and cavie. The Kurloff cell contains a characteristic proteoglycan-containing inclusion body. In the guinea pig, Kurloff cells are more numerous in the adult female than the adult male. A marked increase in the number of circulating Kurloff cells is present in the peripheral blood during pregnancy and after estrogen treatment in male and female animals. A relatively smaller number of cells take place in immature, non-pregnant, and non-estrogen-treated animals. The exact function of Kurloff cells remains unknown, but it has some of the characteristics of both monocytes and lymphocytes. In guinea-pigs, it has been proposed that Kurloff cells mainly involve in the function of the immune system, such as acting as a natural killer cell and preventing damage to the trophoblast by maternal defensive cells. Also, Kurloff cells present antibody-dependent cytotoxic activity in vitro. (en)
- Células Kurloff(também conhecido como Células Foà-Kurloff) são encontradas no sangue e órgãos de porquinhos-da-índia, contêm grandes grânulos secretores (também conhecido como corpos Kurloff) de função desconhecida. Eles também são encontrados em capivaras. Os cientistas especulam que estas células, juntamente com a asparaginase pode ser o que dá aos porquinhos-da-índia propriedades de resistência ao câncer (Sharon Vanderlip, DVM). A célula de Kurloff tem atividade NK citotóxica in vitro. (pt)
|
| dbo:thumbnail
| |
| dbo:wikiPageID
| |
| dbo:wikiPageLength
|
- 11178 (xsd:nonNegativeInteger)
|
| dbo:wikiPageRevisionID
| |
| dbo:wikiPageWikiLink
| |
| dbp:caption
|
- Kurloff cell and a lymphocyte in a Guinea pig (en)
|
| dbp:location
|
- blood and organs of guinea pigs and capybara (en)
|
| dbp:name
| |
| dbp:wikiPageUsesTemplate
| |
| dct:subject
| |
| rdfs:comment
|
- Als Kurloff-Zellen bezeichnet man eine Unterform der weißen Blutkörperchen bei Meerschweinchen. Es handelt sich um mononukleäre Zellen, vor allem Lymphozyten, die durch etwa 8 µm große, in den hämatologischen Standardfärbungen rötliche Einschlusskörperchen (Kurloff-Körperchen) gekennzeichnet sind. Man vermutet, dass Kurloff-Zellen eine besondere Ausprägung der NK-Zellen sind. Der Gehalt des Blutes an Kurloff-Zellen steht bei weiblichen Tieren in Zusammenhang mit dem Östrogenspiegel. Während der Trächtigkeit können sie bis zu 4 % der weißen Blutkörperchen ausmachen. (de)
- Células Kurloff(também conhecido como Células Foà-Kurloff) são encontradas no sangue e órgãos de porquinhos-da-índia, contêm grandes grânulos secretores (também conhecido como corpos Kurloff) de função desconhecida. Eles também são encontrados em capivaras. Os cientistas especulam que estas células, juntamente com a asparaginase pode ser o que dá aos porquinhos-da-índia propriedades de resistência ao câncer (Sharon Vanderlip, DVM). A célula de Kurloff tem atividade NK citotóxica in vitro. (pt)
- Kurloff cells (also known as Foà-Kurloff cells,) were described as mononuclear cells in the peripheral blood and organs of the guinea pig, capybara, paca, agouti and cavie. The Kurloff cell contains a characteristic proteoglycan-containing inclusion body. In the guinea pig, Kurloff cells are more numerous in the adult female than the adult male. A marked increase in the number of circulating Kurloff cells is present in the peripheral blood during pregnancy and after estrogen treatment in male and female animals. A relatively smaller number of cells take place in immature, non-pregnant, and non-estrogen-treated animals. The exact function of Kurloff cells remains unknown, but it has some of the characteristics of both monocytes and lymphocytes. In guinea-pigs, it has been proposed that Kur (en)
|
| rdfs:label
|
- Kurloff-Zelle (de)
- Kurloff cell (en)
- Célula Kurloff (pt)
|
| owl:sameAs
| |
| prov:wasDerivedFrom
| |
| foaf:depiction
| |
| foaf:isPrimaryTopicOf
| |
| is dbo:wikiPageRedirects
of | |
| is dbo:wikiPageWikiLink
of | |
| is foaf:primaryTopic
of | |
