About: 25B-NBOMe

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25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) is a derivative of the phenethylamine psychedelic 2C-B, discovered in 2004 by Ralf Heim at the Free University of Berlin. It acts as a potent full agonist for the 5HT2A receptor. Anecdotal reports from users suggest 25B-NBOMe to be an active hallucinogen at a dose of as little as 250–500 µg, making it a similar potency to other phenethylamine derived hallucinogens such as Bromo-DragonFLY. Duration of effects lasts about 12–16 hours, although the parent compound is rapidly cleared from the blood when used in the radiolabeled form in tracer doses. Recently, Custodio et al (2019) evaluated the potential involvement of dysregulated dopaminergic system, neuroadaptation, and brain wave changes which may contribute to the rewarding and reinforcing

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  • 25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) is a derivative of the phenethylamine psychedelic 2C-B, discovered in 2004 by Ralf Heim at the Free University of Berlin. It acts as a potent full agonist for the 5HT2A receptor. Anecdotal reports from users suggest 25B-NBOMe to be an active hallucinogen at a dose of as little as 250–500 µg, making it a similar potency to other phenethylamine derived hallucinogens such as Bromo-DragonFLY. Duration of effects lasts about 12–16 hours, although the parent compound is rapidly cleared from the blood when used in the radiolabeled form in tracer doses. Recently, Custodio et al (2019) evaluated the potential involvement of dysregulated dopaminergic system, neuroadaptation, and brain wave changes which may contribute to the rewarding and reinforcing properties of 25B-NBOMe in rodents. The carbon-11 labeled version of this compound ([11C]Cimbi-36) was synthesized and validated as a radioactive tracer for positron emission tomography (PET) in Copenhagen. As a 5-HT2A receptor agonist PET radioligand, [11C]Cimbi-36 was hypothesized to provide a more functional marker of these receptors. Also, [11C]Cimbi-36 is investigated as a potential marker of serotonin release and thus could serve as an indicator of serotonin levels in vivo. [11C]Cimbi-36 is now undergoing clinical trials as a PET-ligand in humans. (en)
  • Le 25B-NBOMe (ou 2C-B-NBOMe) est une drogue psychédélique dérivée du 2C-B. Il a été découvert en 2003 à l'université libre de Berlin par le chimiste Ralf Heim. (fr)
  • 25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) — психоактивное вещество из класса фенилэтиламинов, производное от 2C-B, разработанное в 2004 году Ральфом Хеймом в Свободном университете Берлина. Он действует как мощный частичный агонист человеческого рецептора 5-HT2A. Несистематические сообщения от потребителей предполагают, что 25B-NBOMe является активным галлюциногеном в дозе всего лишь 250—500 мкг, что делает его аналогичным по эффективности для других галлюциногенов, полученных из фенилэтиламина, таких как Bromo-DragonFLY. Продолжительность эффекта длится около 12—16 часов. (ru)
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  • 1026511-90-9
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  • Le 25B-NBOMe (ou 2C-B-NBOMe) est une drogue psychédélique dérivée du 2C-B. Il a été découvert en 2003 à l'université libre de Berlin par le chimiste Ralf Heim. (fr)
  • 25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) — психоактивное вещество из класса фенилэтиламинов, производное от 2C-B, разработанное в 2004 году Ральфом Хеймом в Свободном университете Берлина. Он действует как мощный частичный агонист человеческого рецептора 5-HT2A. Несистематические сообщения от потребителей предполагают, что 25B-NBOMe является активным галлюциногеном в дозе всего лишь 250—500 мкг, что делает его аналогичным по эффективности для других галлюциногенов, полученных из фенилэтиламина, таких как Bromo-DragonFLY. Продолжительность эффекта длится около 12—16 часов. (ru)
  • 25B-NBOMe (NBOMe-2C-B, Cimbi-36, Nova, BOM 2-CB) is a derivative of the phenethylamine psychedelic 2C-B, discovered in 2004 by Ralf Heim at the Free University of Berlin. It acts as a potent full agonist for the 5HT2A receptor. Anecdotal reports from users suggest 25B-NBOMe to be an active hallucinogen at a dose of as little as 250–500 µg, making it a similar potency to other phenethylamine derived hallucinogens such as Bromo-DragonFLY. Duration of effects lasts about 12–16 hours, although the parent compound is rapidly cleared from the blood when used in the radiolabeled form in tracer doses. Recently, Custodio et al (2019) evaluated the potential involvement of dysregulated dopaminergic system, neuroadaptation, and brain wave changes which may contribute to the rewarding and reinforcing (en)
rdfs:label
  • 25B-NBOMe (en)
  • 25B-NBOMe (fr)
  • 25B-NBOMe (ru)
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