Continuous glucose monitoring versus conventional glucose monitoring in the ICU: A randomized controlled trial
- PMID: 39106581
- DOI: 10.1016/j.jcrc.2024.154894
Continuous glucose monitoring versus conventional glucose monitoring in the ICU: A randomized controlled trial
Abstract
Purpose: This study evaluated the clinical utility of continuous glucose monitoring system (CGMS) in critically ill patients.
Methods: In this randomized controlled trial, we randomly assigned critically ill participants with diabetes or stress-induced hyperglycemia to the CGMS group (n = 48) or to the conventional point-of-care monitoring (POCM) group (n = 48). The glucose values and clinical outcome were compared between the two group. The primary endpoint was 28-day mortality after intensive care unit admission.
Results: The 28-day mortality was not significantly different between the CGMS and POCM group (20.8% vs 31.3%, P = 0.25). The mean glucose, time-weighted average glucose, glucose standard deviation and time in range (3.9-10.0) were significantly improved in the CGMS group (all P < 0.05).
Conclusion: Compared with conventional POCM, CGMS did not decrease the 28-day mortality in critically ill participants with diabetes or stress-induced hyperglycemia. But CGMS may improve the glycemic control and may be increasingly used in critically ill patients.
Keywords: Continuous glucose monitoring system; Glycemic variability; Intensive care unit; Mortality.
Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of competing interest The authors declare that there are no potential conflicts of interest.
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