The Dermatology Digest

Explore the new TDD supplement for the latest thinking on treating transitional skin, including adult acne and the signs of pre-aging. thedermdigest.com

Organon is acquiring Dermavant Sciences Ltd. Dermavant’s novel product, tapinarof cream, 1% (Vtama) for the topical treatment of mild, moderate, and severe plaque psoriasis in adults, was approved by the U.S. FDA in May 2022. The FDA is reviewing a Supplemental New Drug Application (sNDA) for tapinarof cream, 1% as a potential treatment for atopic dermatitis (AD) in adults and children two years of age and older, with Prescription Drug User Fee Act (PDUFA) action expected in the fourth quarter of calendar year 2024. https://lnkd.in/dqBFizFN

JACQUELINE WATCHMAKER, MD, a dermatologist in Scottsdale, AZ, pays homage to everyone’s favorite anti-ager as part of the first-ever National Retinoid Week. She also shares some of her favorite retinoids. skinbetter science launched #RetinoidWeek. https://lnkd.in/d5cshtrk

One in four people with psoriasis may show early signs of psoriatic arthritis, according to initial results from the Hippocrates Prospective Observational Study (HPOS). The study is conducted by researchers at University College Dublin in partnership with the University of Oxford and aims to monitor people with psoriasis to see if psoriatic arthritis can be spotted and treated earlier. So far, approximately 1,500 participants have registered and completed an online evaluation tool. https://lnkd.in/dt84cwv2

About half of patients with metastatic melanoma treated with a combination of immune checkpoint inhibitors survive cancer-free for 10 years or more, according to follow-up data from CheckMate -067 presented at the ESMO - European Society for Medical Oncology Congress 2024 in Barcelona, Spain and simultaneously published in The New England Journal of Medicine. https://lnkd.in/dsXRhnkv  Jedd Wolchok, MD, PhD

Joel M Gelfand MD MSCE, Carol Ostrow, and Jose U. Scher, MD, will be honored at The National Psoriasis Foundation 2025 Commit to Cure Gala in New York City. https://lnkd.in/d2K2Bv-b

The U.S. FDA has approved lebrikizumab-lbkz (Ebglyss, Lilly), a targeted interleukin (IL)-13 inhibitor, for the treatment of adults and children 12 years of age and older who weigh at least 88 pounds (40kg) with moderate-to-severe #atopicdermatitis (eczema) that is not well controlled despite treatment with topical prescription therapies. https://lnkd.in/d4QMGNMj

Steve Clark, 81, passed away on September 8, 2024. He served as the President of Galderma Laboratories from 1985-2001, making it one of the most successful #dermatology companies in the world by acquiring, developing, and launching notable products such as MetroGel, Differen Triluma, Desowen, Benzac, and the Cetaphil product line, among others. In 2003, after retiring from Galderma, Mr. Clark became the President of Coria Laboratories, which was a launchpad for Cerave skincare. https://lnkd.in/dPkNb9mt Suzanne Lane

In the Level Up study, upadacitinib (Rinvoq, AbbVie) bested dupilumab (Dupixent, Regeneron and Sanofi) in the primary endpoint, demonstrating that a significantly higher proportion of #atopicdermatitis (AD)patients simultaneously achieved both a 90% or greater reduction in Eczema Area and Severity Index (EASI 90) and a Worst Pruritus Numerical Rating Scale of 0 or 1(WP-NRS 0/1) at Week 16. Level-Up Investigator Christopher Bunick, MD, PhD, an Associate Professor of Dermatology at Yale University in New Haven, CT, reviews the data and explains how these findings help elevate the standard of care in AD. https://lnkd.in/ddBBvyDK

Leading #dermatologists and facial plastic surgeons are sounding the alarm about a perilous social media trend: self-injections with unapproved soft tissue fillers. Growing numbers of consumers are purchasing unapproved soft tissue fillers online and injecting their own lips, cheeks, and under-eye hollows.  Many videos feature non-experts describing DIY injection techniques while glossing over or ignoring such risks as bruising, redness, swelling, skin and soft tissue infections, tissue death, and even blindness. https://lnkd.in/dUnqh92J