Oprah Winfrey

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Laura Jacobs heralds a new era for women of achievement.

This collection of bits of wisdom begins with Oprah Winfrey recalling a 1998 interview during which the late, great film critic Gene Siskel asked her, “[W]hat do you know for sure?” “Now, this was not my first rodeo,” Oprah writes. “I’ve asked and been asked an awful lot of questions over the years . . . but I have to say, the man managed to stop me in my tracks.” In the years following that interview, Oprah wrote monthly columns called “What I Know for Sure” in her eponymous magazine.

THR photographed the media mogul at her Montecito, Calif., home.

Oprah Winfrey's new documentary “The Color of Care” is premiering on Sunday. Ahead of the release she shared her own experience in the healthcare system.

The media mogul will accept the Golden Globes' top honor at next month's ceremony.

Stranger things have happened

The inspiration

Everything you really need to know about menopause. WHAT I KNOW FOR SURE For two years, I didn’t sleep well. Never a full night. No peace. Restlessness and heart palpitations were my steady companions at nightfall. This was back when I was 48 to 50. I went to see a cardiologist. Took medication. Wore a heart monitor for weeks. And then one day, walking through the offices of The Oprah Winfrey Show, I picked up a copy of The Wisdom of Menopause, Dr. Christiane Northrup’s book, and the pages…