SM-Youtube

1

Crystal structure of subunits D and F in complex gives insight into energy transmission of the eukaryotic V-ATPase from Saccharomyces cerevisiae.

Balakrishna AM, Basak S, Manimekalai MS, Grüber G. Balakrishna AM, et al. Among authors: manimekalai ms. J Biol Chem. 2015 Feb 6;290(6):3183-96. doi: 10.1074/jbc.M114.622688. Epub 2014 Dec 12. J Biol Chem. 2015. PMID: 25505269 Free PMC article.

2

Spectroscopic and crystallographic studies of the mutant R416W give insight into the nucleotide binding traits of subunit B of the A1Ao ATP synthase.

Kumar A, Manimekalai MS, Balakrishna AM, Hunke C, Weigelt S, Sewald N, Grüber G. Kumar A, et al. Among authors: manimekalai ms. Proteins. 2009 Jun;75(4):807-19. doi: 10.1002/prot.22289. Proteins. 2009. PMID: 19003877

3

Structure of the nucleotide-binding subunit B of the energy producer A1A0 ATP synthase in complex with adenosine diphosphate.

Kumar A, Manimekalai MS, Grüber G. Kumar A, et al. Among authors: manimekalai ms. Acta Crystallogr D Biol Crystallogr. 2008 Nov;64(Pt 11):1110-5. doi: 10.1107/S090744490802790X. Epub 2008 Oct 18. Acta Crystallogr D Biol Crystallogr. 2008. PMID: 19020348

4

A second transient position of ATP on its trail to the nucleotide-binding site of subunit B of the motor protein A(1)A(0) ATP synthase.

Manimekalai MS, Kumar A, Balakrishna AM, Grüber G. Manimekalai MS, et al. J Struct Biol. 2009 Apr;166(1):38-45. doi: 10.1016/j.jsb.2008.12.004. Epub 2008 Dec 24. J Struct Biol. 2009. PMID: 19138746

5

Nucleotide binding states of subunit A of the A-ATP synthase and the implication of P-loop switch in evolution.

Kumar A, Manimekalai MS, Balakrishna AM, Jeyakanthan J, Grüber G. Kumar A, et al. Among authors: manimekalai ms. J Mol Biol. 2010 Feb 19;396(2):301-20. doi: 10.1016/j.jmb.2009.11.046. Epub 2009 Nov 26. J Mol Biol. 2010. PMID: 19944110

6

Crystal and solution structure of the C-terminal part of the Methanocaldococcus jannaschii A1AO ATP synthase subunit E revealed by X-ray diffraction and small-angle X-ray scattering.

Balakrishna AM, Manimekalai MS, Hunke C, Gayen S, Rössle M, Jeyakanthan J, Grüber G. Balakrishna AM, et al. Among authors: manimekalai ms. J Bioenerg Biomembr. 2010 Aug;42(4):311-20. doi: 10.1007/s10863-010-9298-3. Epub 2010 Jun 23. J Bioenerg Biomembr. 2010. PMID: 20571891

7

The critical roles of residues P235 and F236 of subunit A of the motor protein A-ATP synthase in P-loop formation and nucleotide binding.

Kumar A, Manimekalai MS, Balakrishna AM, Priya R, Biuković G, Jeyakanthan J, Grüber G. Kumar A, et al. Among authors: manimekalai ms. J Mol Biol. 2010 Sep 3;401(5):892-905. doi: 10.1016/j.jmb.2010.06.070. Epub 2010 Jul 6. J Mol Biol. 2010. PMID: 20615420

8

Crystallization and preliminary X-ray crystallographic analysis of subunit F (F(1-94)), an essential coupling subunit of the eukaryotic V(1)V(O)-ATPase from Saccharomyces cerevisiae.

Basak S, Balakrishna AM, Manimekalai MS, Grüber G. Basak S, et al. Among authors: manimekalai ms. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Sep 1;68(Pt 9):1055-9. doi: 10.1107/S1744309112032526. Epub 2012 Aug 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22949193 Free PMC article.

9

Crystal and NMR structures give insights into the role and dynamics of subunit F of the eukaryotic V-ATPase from Saccharomyces cerevisiae.

Basak S, Lim J, Manimekalai MS, Balakrishna AM, Grüber G. Basak S, et al. Among authors: manimekalai ms. J Biol Chem. 2013 Apr 26;288(17):11930-9. doi: 10.1074/jbc.M113.461533. Epub 2013 Mar 8. J Biol Chem. 2013. PMID: 23476018 Free PMC article.

10

Protein-protein interactions within the ensemble, eukaryotic V-ATPase, and its concerted interactions with cellular machineries.

Balakrishna AM, Manimekalai MS, Grüber G. Balakrishna AM, et al. Among authors: manimekalai ms. Prog Biophys Mol Biol. 2015 Oct;119(1):84-93. doi: 10.1016/j.pbiomolbio.2015.05.003. Epub 2015 May 29. Prog Biophys Mol Biol. 2015. PMID: 26033199 Review.

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