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- A drama series centred on the lives of the nurses at All Saints Western General Hospital.
- Terri faces the final day of her trial with Mitch as her star witness. Kylie and Jared investigate a woman who had an allergic reaction to sex.
- Mitch goes to great personal and professional lengths to diagnose the illness of an aspiring Olympic athlete. Bronwyn learns an important lesson about herself.
- Luke's estranged younger brother is admitted to the ward after swallowing razor-blades to temporarily get out of prison.
- Luke is put through the wringer when a patient deteriorates before his eyes. Jared learns more harsh truths about Angie.
- The rapist strikes again, kidnapping Bron and leaving a young nurse dead. Ward 17 is threatened with quarantine after a breakout of golden staph amongst patients. Luke is forbidden to operate on patients after being suspected as a golden staph carrier. In mortal danger, Bron is shocked when she discovers the identity of the serial rapist.
- Terri finds herself unable to separate professional ethics from her personal beliefs when a witch is admitted to the ward.
- Any thoughts of a quiet day are quashed as the Ambulance Bay doors crash open delivering Jamie and his mum Karen from one motor vehicle accident, closely followed by Kent, a cyclist who's gone under a bus. Moving from one medical crisis to another, the staff marvel at the fact Kent made it through the doors at all. Jamie and Karen are known to the Emergency Department staff and Von and Charlotte bonded with them the last time they visited [episodes 7.38 and 7.39]. Back then Karen, was denying the tragic deaths of her husband and daughter three months earlier. This time, the pair has been in a motor vehicle accident and shortly after reaching the Emergency Department Karen has a psychotic episode, forcing some of the All Saints team into unfamiliar territory. Throughout the course of the day, Jamie opens up about the incredible burden he's been under as sole carer for his mum; a burden a 17-year-old kid should never have to face alone. Meanwhile, Nelson has recently been reunited with his daughter and at last a relationship is forming and Dan grows increasingly angry at having to keep Stuart's return a secret from Jessica. Vincent and Charlotte finally come to the realisation they're not married any more, brought on by an increasing attraction between Vincent and Cate.
- Sarah Adams' health is failing fast and the fight to keep her alive through the compensation case proceedings takes its emotional toll on Mitch and Kate. Bron's gambling debts have escalated to a point that her loan shark, wanting to recoup his loss, suggests that Bron steal pethidine off the ward. Scott missed breakfast after a wild night of passion causing him and Ben to be at each other's throat. Tempers fray when they are called to a biscuit factory where one of the workers has collapsed. Meanwhile Connor is struggling to find out why he is suddenly in the bad books with Jodi.
- While Stephanie tries to adjust to the idea of being pregnant, she is assigned to nurse a dying woman who wants to hold on for the birth of her grandchild.
- The permanent closure of ward 17 heralds the end of an era and generates much uncertainty among the nursing staff.
- Bron faces the dilemma of becoming too attached to a patient. Jared discovers that Angie lied to him about continuing her out-patients treatment. Terri goes into battle with the bureaucrats.
- Terri is locked up at the local police station after being charged with the murder of Rose Stevens.
- At a run down city club, an off-duty female All Saints staff member is given illegal party drugs, in her drink, causing her to foolishly dance in front of lusting male club goers.
- It is a race against time when Luke and Terri are forced to help a patient overcome his phobia about hospitals in order to get him into theatre for life-saving surgery.
- As the All Saints staff are kicking up their heels at the Hospital Fundraising Ball, Terri battles an obsessed ex-patient.
- Terri struggles to deal with what has happened to her friends. Bronwyn learns about the hierarchy in the ambulance organisation.
- Mitch and Rose must decide their future - stay together or divorce? Mitch tells Terri he has made the difficult decision on whether or not he'll divorce Rose. Breaking all the rules, Paula rejects Terri and Luke's orders on how to care for a patient that she has become emotionally attached to. Kylie saves the day with her hand down a patient's throat.
- Today is the day of Mitch's brain biopsy. A Multiple Sclerosis sufferer has reached the end of her road.
- After spending the night with Mitch Terri takes a 'sickie'. Nelson, acting NUM in Terri's absence, urges the others to a team effort. Bron returns from England to a bizarre welcome from Jared and Scott who feud over Jared's interference with Scott's study. Von plays matchmaker when she realises that an MVA patient has fallen in love with an East Timorese girl he has married so that she can obtain permanent residency in Australia. Ben and Rebecca attend to a forklift operator trapped beneath fallen newsprint rolls which stops Ben being able to pick up Bron at the airport.
- Connor wrestles with the fear that his mother has contracted a very serious illness , with the rules of patient confidentiality, and with the suspicion that his brother or his mum's boyfriend is responsible for her illness. Bron confronts her own issues with her childhood and her father when a young man is admitted after slashing his wrists. The father seems completely uninterested in visiting him or communicating with him in any way. Scott organises a birthday treat for Ben - a raunchy on-stage tango with a lingerie waitress.
- It's a heartbreaking time for Samantha when her mother's condition worsens. Mitch uses his voodoo skills to help a deluded patient.
- Suffering from morning sickness, Terri's day turns sour when she's caught in the crossfire of a bitter dispute between Mitch and Charlotte after one of his clinic patients is admitted to the ward following an overdose. Paula is forced to consider medicating her son Max to ease his behavioural problems after he hijacks an ambulance. With their first baby on the way, Terri and Mitch decide it's time to move in together - and they soon find the perfect home. Bron's unhappy personal life interferes with her work. Von finds she cannot distance herself from her young friend Adam who makes his way back to the ward.
- Von tries to hide her secret past when she encounters a patient who remembers her from 30 years ago.
- Terri and Peter are forced to put a young girl's emotional health at risk in order to save the life of a newborn baby. Jared is thrilled by Angie's attempts to get her life back on track.